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　　Leila偶然发现了隐藏在她最喜爱的虚拟现实游戏Azana中的「红色药丸」—— 一个绝密的天堂。母亲去世后，Leila陷入了深深的孤独感。所幸她为自己创造了一个数字身份「影疾」，可以在游戏世界中暂时忘掉烦恼。每当登入虚拟现实游戏Azana之后，她才感觉自己真正活着。在这个令 人惊叹的虚拟之地，Leila遇到了神秘的游戏角色Mania，她拥有Leila所没有的一切：快乐主义、任性、永不知足。当Leila发现秘密天堂「红色药丸」之后，「红色药丸」的领袖Adrian声称她不可以不请自来，然后将她的数字角色「影疾」赶出了游戏。第二天，Mania——或者说Mania的现实生活身份Tess——竟然出现在Leila工作的地方，从此进入Leila的现实生活，Leila的世界永远被改变了。Leila很快意识到，所谓的虚拟天堂不是神秘庇护所，也不是Adrian所声称的美好之地。但她更想知道Tess/Mania究竟是怎么回事……

　　第三季着眼于艾米莉·狄金森作为一名艺术家最富有成效的时期，发生在正在进行的美国内战和一场分裂她自己家庭的激烈战斗之间。

　　Having woken up in Hong Kong, with no memory for the last two years (!), Sydney returns to Los Angeles to try to piece together the last two years of her life and discovers the fates of her friends and family: Vaughn has married thinking that Sydney was long dead Marshall is having a baby with CIA tech expert Carrie Bowman and Dixon is now the new division head of the L.A. office branch of the CIA. Sydney also learns the shocking fates of Jack and Sloane the former is in CIA custody for communicating with Irina whom still is in hiding, while the latter is living in Switzerland under house arrest in exchange for co-operation with the CIA. Sydney is granted temporary CIA clearance on a case that may help her regain her memory and she meets a new enemy group called The Covenant.