Centers on two mysterious brothers, who abduct a mogul during his quest for immortality. Meanwhile, a seductive woman helps them launch a journey of self-discovery.
Alex, a sound engineer, accidentally records mysterious voices: disturbing messages from the afterlife who warn him against an imminent and terrifying danger. Amanda, with whom he shares a terrible secret, re-emerges from his past. The appearance of the young woman triggers chilling paranormal phenomena that leave behind a trail of corpses. Is she the danger the voices of the dead speak about?
故事发生在1956年的法国，一名牧师惨遭谋杀，某种邪恶正在散播，艾琳修女（泰莎·法米加 Taissa Farmiga 饰）将再次与鬼修女瓦拉克（邦妮·阿伦斯 Bonnie Aarons 饰）展开正面对决。
一对在孕期的夫妇Jack（罗伯·考德瑞 饰）和Vanessa（莱丝莉·比伯 饰）因为生活所迫，从原来的城市搬到了新奥尔良的一个小镇上，并意外住进了这个小镇上闹鬼最厉害的房子。Jack夫妇刚住进房子时非常开心，甚至已经规划好了未来的美好生活，可是这份喜悦并没有持续多久就被奇怪的邻居F'resnel（科甘·迈克尔·基 饰）破坏了。他们也在之后见到了这个房子里的魔鬼，并开始寻求梵蒂冈的驱魔精英团队的帮助，希望可以摆脱恶魔。
这部电影将六个故事组合成一个综合系列，描绘了由于人类错误的欲望而发生的奇异事件。
